
ASTHMA
What is Asthma?
Asthma is a chronic inflammatory disorder of the airways in which many cells and cellular elements play a role.
In susceptible individuals, this inflammation causes recurrent episodes of:
These episodes are associated with airflow obstruction (excessive airway narrowing) that is often reversible either
spontaneously or with treatment. This airflow obstruction is the result of contraction of the airway smooth muscle and
swelling of the airway wall
Risk factors for the development of asthma
Trigger factors for asthma
If people with asthma understand that asthma is caused by more than bronchospasm, they will appreciate the need for separate types of medication for asthma management:
Signs and symptoms of asthma vary widely from person to person and the absence of typical symptoms does not
exclude the diagnosis of asthma. Community pharmacists should seek all relevant information from the patient’s history
when confronted with any of the symptoms discussed earlier.
Bronchodilator medications
Bronchodilators relax bronchial smooth muscle and hence allow widening of airways. They provide mainly symptomatic
relief and are first line treatment for acute asthma attacks.
In
§ Salbutamol (Epaq, Ventolin, Airomir & Asmol) MDI (metered dose inhaler)
Inhale 1-2 doses by mouth as required, repeat 3-4 times a day if needed.
§ Terbutaline (Bricanyl turbuhaler)
Inhale 1-2 doses by mouth as required, repeat 3-4 times a day if needed.
Common side effects of bronchodilators:
Tremor, palpitations, headache, agitation and infrequently hyperactivity in children.